Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16477985 | 0.87 | KDM4E (0.45) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL19072011 | 0.84 | KDM4E (0.54) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL14148344 | 0.81 | MAPT (0.50) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL18589990 | 0.80 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL19261444 | 0.80 | PGR (0.35) | KDM4E | |
| SCHEMBL19072010 | 0.80 | KDM4E (0.40) | MAPTKDM4EHTTHPGDLMNA | |
| SCHEMBL6060767 | 0.77 | PDK2 (0.40) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14735970 | 0.77 | PDK2 (0.40) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6060800 | 0.77 | PDK2 (0.40) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6060780 | 0.77 | PDK2 (0.40) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714659-B1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | AMERICAN DYE SOURCE INC (CA) | 2017-07-05 | — | — | EP | disclosed |