Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL28786996 | 0.93 | TSHR (0.55) | TSHRALDH1A1TDP1FAAHCES2 | |
| Carbamic Acid SCHEMBL11497585 | 0.92 | TSHR (0.60) | TSHRALDH1A1TDP1FAAHCES2 | |
| SCHEMBL28536289 | 0.92 | TSHR (0.60) | TSHRALDH1A1TDP1FAAHCES2 | |
| Urea SCHEMBL28096148 | 0.91 | TSHR (0.52) | TSHRALDH1A1TDP1FAAHCES2 | |
| Carbamic Acid SCHEMBL27915395 | 0.90 | TSHR (0.57) | TSHRALDH1A1TDP1FAAHCES2 | |
| Carbamic Acid SCHEMBL10844466 | 0.90 | TSHR (0.65) | TSHRALDH1A1TDP1FAAHCES2 | |
| Aminomethylamide SCHEMBL28857413 | 0.87 | TSHR (0.55) | TSHRALDH1A1TDP1FAAHCES2 | |
| SCHEMBL27759501 | 0.86 | TSHR (0.67) | TSHRALDH1A1TDP1FAAHCES2 | |
| Acetone SCHEMBL27529878 | 0.86 | TSHR (0.67) | TSHRALDH1A1TDP1FAAHCES2 | |
| Bicarbonate SCHEMBL38662423 | 0.86 | TSHR (0.67) | TSHRALDH1A1TDP1FAAHCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108434962-A | A kind of equipment for treating industrial waste gas | 芜湖乐知智能科技有限公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-108026055-A | 2,4,6- tri-（2- hydroxy-3-methyl -4- alkoxyl phenyls）- 1,3,5- triaizine compounds and 2,4,6- tri-（2,4- dihydroxy -3- aminomethyl phenyls）The manufacture method of -1,3,5- triazines | 株式会社钟化 | 2018-05-11 | — | — | CN | disclosed |
| CN-106554293-B | A kind of method for preparing colourless or light polyisocyanates | 万华化学集团股份有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-106554293-A | A kind of method for preparing colourless or light polyisocyanates | 万华化学集团股份有限公司 | 2017-04-05 | — | — | CN | disclosed |
| EP-2489660-A1 | Methods for making central nervous system agents that are TRPV1 antagonists | Abbott Laboratories (US) | 2012-08-22 | — | — | EP | disclosed |
| US-8232411-B2 | Methods for making central nervous system agents that are TRPV1 antagonists | ABBOTT LABORATORIES (US) | 2012-07-31 | — | — | US | disclosed |
| EP-2323989-A2 | METHODS FOR MAKING CENTRAL NERVOUS SYSTEM AGENTS THAT ARE TRPV1 ANTAGONISTS | Abbott Laboratories (US) | 2011-05-25 | — | — | EP | disclosed |
| CN-102036969-A | Methods for making central nervous system agents that are TRPV1 antagonists | ABBOTT LAB | 2011-04-27 | — | — | CN | disclosed |
| US-20100016611-A1 | METHODS FOR MAKING CENTRAL NERVOUS SYSTEM AGENTS THAT ARE TRPV1 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2010-01-21 | — | — | US | disclosed |
| WO-2009117626-A2 | METHODS FOR MAKING CENTRAL NERVOUS SYSTEM AGENTS THAT ARE TRPV1 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2009-09-24 | — | — | WO | disclosed |
| CN-1793346-A | Corn SOD molecular modifying agent and modifying process thereof | SHENYANG AGRICULTURE UNIV (CN) | 2006-06-28 | — | — | CN | disclosed |
| CN-1032184-C | Fungicides and process for preparing same | ICI PLC (GB) | 1996-07-03 | — | — | CN | disclosed |
| CN-1048383-A | Mycocide and preparation method thereof | ICI PLC (GB) | 1991-01-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016611-A1 | METHODS FOR MAKING CENTRAL NERVOUS SYSTEM AGENTS THAT ARE TRPV1 ANTAGONISTS | TRPV1, TRPV2, OPRL1 | TSHR 4186/4885ALDH1A1 499/4885TDP1 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.