Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 20/20 | 0.68 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19082665 | 1.00 | CACNA1H (0.68) | CACNA1HCACNA1GCACNA1BCACNA1C | |
| SCHEMBL18716582 | 1.00 | CACNA1H (0.68) | CACNA1HCACNA1GCACNA1BCACNA1C | |
| SCHEMBL19082674 | 0.97 | CACNA1H (0.66) | CACNA1HCACNA1GCACNA1BCACNA1C | |
| SCHEMBL19082673 | 0.93 | CACNA1H (0.68) | CACNA1HCACNA1GCACNA1BCACNA1C | |
| SCHEMBL19082677 | 0.86 | CACNA1H (0.51) | CACNA1HCACNA1GCACNA1BCACNA1C | |
| SCHEMBL17309075 | 0.86 | CACNA1H (0.49) | CACNA1HCACNA1GCACNA1BCACNA1C | |
| SCHEMBL19082658 | 0.85 | CACNA1H (0.49) | CACNA1HCACNA1GCACNA1BCACNA1C | |
| SCHEMBL18686693 | 0.81 | CACNA1H (1.00) | CACNA1HCACNA1GCACNA1BCACNA1C | |
| SCHEMBL18686561 | 0.81 | CACNA1H (1.00) | CACNA1HCACNA1GCACNA1BCACNA1C | |
| SCHEMBL18686560 | 0.81 | CACNA1H (1.00) | CACNA1HCACNA1GCACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856250-B2 | Substituted tropane derivatives | TOA EIYO LTD. (JP) | 2018-01-02 | — | — | US | disclosed |
| US-20170190699-A1 | SUBSTITUTED TROPANE DERIVATIVES | TOA EIYO LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
| US-20170190699-A1 | SUBSTITUTED TROPANE DERIVATIVES | TOA EIYO LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190699-A1 | SUBSTITUTED TROPANE DERIVATIVES | CACNA1G, CACNA1H, CACNA1I | CACNA1H 2/4885CACNA1G 1/4885CACNA1B 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.