Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903392 | 0.93 | TRPA1 (0.34) | ALOX5APFEN1TRPA1MAPTKDM4E | |
| SCHEMBL1905679 | 0.91 | ALOX5AP (0.31) | ALOX5APFEN1TRPA1MAPTKDM4E | |
| SCHEMBL1905301 | 0.91 | — | — | |
| SCHEMBL1905491 | 0.91 | ALOX5AP (0.32) | ALOX5APFEN1TRPA1 | |
| SCHEMBL1906374 | 0.89 | HTR2C (0.34) | MAPT | |
| SCHEMBL1905160 | 0.89 | ALOX5AP (0.31) | ALOX5APFEN1TRPA1 | |
| SCHEMBL1902985 | 0.87 | CXCR5 (0.35) | ALOX5APFEN1TRPA1MAPTKDM4E | |
| SCHEMBL1904364 | 0.86 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL1904947 | 0.85 | — | — | |
| SCHEMBL1905157 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118427-A1 | Transition Metal Complex And Process For Production Thereof, Olefin Polymerization Catalyst, Process For Production of Polyolefin Resin, And Substituted Fluorene Compound And Process For Production Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118427-A1 | Transition Metal Complex And Process For Production Thereof, Olefin Polymerization Catalyst, Process For Production of Polyolefin Resin, And Substituted Fluorene Compound And Process For Production Thereof | FIP1L1, FDFT1, COASY | ALOX5AP 285/4885FEN1 2861/4885TRPA1 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.