Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050310 | 0.90 | — | — | |
| SCHEMBL12224196 | 0.82 | NAAA (0.51) | POLBNAAAKMT2AALDH1A1HSD17B10 | |
| SCHEMBL17208374 | 0.82 | NAAA (0.51) | POLBNAAAKMT2AALDH1A1HSD17B10 | |
| SCHEMBL16727379 | 0.82 | NAAA (0.43) | POLBNAAAKMT2AALDH1A1HSD17B10 | |
| SCHEMBL15199112 | 0.82 | NAAA (0.51) | POLBNAAAKMT2AALDH1A1HSD17B10 | |
| SCHEMBL14327357 | 0.82 | NAAA (0.43) | POLBNAAAKMT2AALDH1A1HSD17B10 | |
| SCHEMBL16727370 | 0.81 | POLB (0.53) | POLBNAAAKMT2AALDH1A1HSD17B10 | |
| SCHEMBL23595437 | 0.80 | NAAA (0.58) | NAAAKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL19093034 | 0.79 | NAAA (0.62) | NAAAKMT2AALDH1A1GNAI3GNAO1 | |
| SCHEMBL15431471 | 0.79 | NAAA (0.49) | POLBNAAAKMT2AGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017117275-A1 | SILICA NANOPARTICLE WITH PLATINUM ANTI-CANCER AGENT | CITY OF HOPE (US) | 2017-07-06 | — | — | WO | disclosed |