Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386157 | 0.83 | GPR119 (1.00) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390409 | 0.83 | GPR119 (0.87) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389837 | 0.82 | GPR119 (0.82) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389323 | 0.82 | GPR119 (1.00) | GPR119CYP2C9KCNH2 | |
| SCHEMBL29376677 | 0.82 | GPR119 (1.00) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389125 | 0.78 | GPR119 (0.70) | GPR119CYP2C9KCNH2 | |
| SCHEMBL391113 | 0.76 | GPR119 (0.80) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389757 | 0.75 | GPR119 (0.87) | GPR119CYP2C9KCNH2 | |
| SCHEMBL388014 | 0.75 | GPR119 (0.74) | GPR119CYP2C9KCNH2 | |
| SCHEMBL12505331 | 0.74 | GPR119 (0.78) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322157-A1 | Composition for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood GLP-1 level | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |