Styrene

Styrene

SCHEMBL19084984

C=CC(=O)O.C=CC=C.C=Cc1ccccc1.O=C(O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Styrene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
TSHR P16473 1/20 0.61
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
AKT1 P31749 1/20 0.45
TNKS O95271 1/20 0.45
HCAR2 Q8TDS4 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
TNKS2 Q9H2K2 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
LMNA P02545 2/20 0.43
TGM2 P21980 1/20 0.41
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL343053 0.98 ALDH1A1 (0.64) ALDH1A1TSHRHDAC3HDAC4HDAC1
Styrene SCHEMBL9407349 0.98 ALDH1A1 (0.64) ALDH1A1TSHRHDAC3HDAC4HDAC1
Styrene SCHEMBL17180460 0.93 ALDH1A1 (0.70) ALDH1A1TSHRHDAC3HDAC4HDAC1
Styrene SCHEMBL28179846 0.93 ALDH1A1 (0.70) ALDH1A1TSHRHDAC3HDAC4HDAC1
Styrene SCHEMBL679822 0.93 ALDH1A1 (0.70) ALDH1A1TSHRHDAC3HDAC4HDAC1
Styrene SCHEMBL11061627 0.93 ALDH1A1 (0.70) ALDH1A1TSHRHDAC3HDAC4HDAC1
Styrene SCHEMBL9064473 0.93 ALDH1A1 (0.70) ALDH1A1TSHRHDAC3HDAC4HDAC1
Styrene SCHEMBL5175970 0.93 ALDH1A1 (0.70) ALDH1A1TSHRHDAC3HDAC4HDAC1
Styrene SCHEMBL27702684 0.93 ALDH1A1 (0.70) ALDH1A1TSHRHDAC3HDAC4HDAC1
Styrene SCHEMBL60237 0.93 ALDH1A1 (0.70) ALDH1A1TSHRHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170267911-A1 OIL ABSORBENT OILFIELD MATERIALS AS ADDITIVES IN OIL-BASED DRILLING FLUID APPLICATIONS HALLIBURTON ENERGY SERVICES, INC. 2017-09-21 US claimed
US-9701881-B2 Oil absorbent oilfield materials as additives in oil-based drilling fluid applications HALLIBURTON ENERGY SERVICES, INC. (US) 2017-07-11 US claimed
EP-3372437-B1 USER INTERFACE APPARATUS FOR VEHICLE, METHOD OF MANUFACTURING USER INTERFACE APPARATUS, AND VEHICLE LG ELECTRONICS INC (KR) 2019-05-15 EP disclosed
US-10202040-B2 User interface apparatus for vehicle, method of manufacturing user interface apparatus, and vehicle LG ELECTRONICS INC. (KR) 2019-02-12 US disclosed
CN-108528363-A Vehicle user's interface device and its manufacturing method and vehicle LG电子株式会社 2018-09-14 CN disclosed
EP-3372437-A1 USER INTERFACE APPARATUS FOR VEHICLE, METHOD OF MANUFACTURING USER INTERFACE APPARATUS, AND VEHICLE LG Electronics Inc. (KR) 2018-09-12 EP disclosed
US-20180251032-A1 USER INTERFACE APPARATUS FOR VEHICLE, METHOD OF MANUFACTURING USER INTERFACE APPARATUS, AND VEHICLE LG ELECTRONICS INC. (KR) 2018-09-06 US disclosed
CN-106994946-A Vehicle user's interface device and vehicle LG电子株式会社 2017-08-01 CN disclosed