Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.62 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.57 |
| ▸ | WNT3A | P56704 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.51 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404361 | 0.89 | MAOB (0.59) | MAOBMETTL3CTNNB1WNT3ANPC1 | |
| SCHEMBL5441326 | 0.84 | MAOB (0.79) | MAOBMETTL3CTNNB1WNT3AROCK2 | |
| SCHEMBL5407158 | 0.84 | MAOB (0.60) | MAOBMETTL3CTNNB1WNT3ANPC1 | |
| SCHEMBL13373522 | 0.83 | MAOB (0.57) | MAOBMETTL3CTNNB1WNT3ANPC1 | |
| SCHEMBL5415946 | 0.83 | MAOB (0.57) | MAOBMETTL3CTNNB1WNT3ANPC1 | |
| SCHEMBL3493150 | 0.83 | MAOB (0.59) | MAOBMETTL3CTNNB1WNT3ANPC1 | |
| SCHEMBL5409154 | 0.83 | MAOB (0.59) | MAOBMETTL3CTNNB1WNT3ANPC1 | |
| SCHEMBL5415980 | 0.82 | HTT (0.56) | MAOBMETTL3CTNNB1WNT3ANPC1 | |
| SCHEMBL5413397 | 0.82 | MAOB (0.56) | MAOBMETTL3CTNNB1WNT3AMAOA | |
| SCHEMBL10325569 | 0.82 | CTNNB1 (0.53) | MAOBMETTL3CTNNB1WNT3ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114275-A1 | COMPOUND FOR INHIBITING ROCK, PREPARATION METHOD AND USE OF SAME | 成都先导药物开发有限公司 | 2017-07-06 | — | — | WO | disclosed |