Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.53 |
| ▸ | WNT3A | P56704 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.48 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19086030 | 0.82 | MAOB (0.62) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL3493150 | 0.80 | MAOB (0.59) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL5409154 | 0.80 | MAOB (0.59) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL5404361 | 0.80 | MAOB (0.59) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL4404815 | 0.77 | CTNNB1 (0.69) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL5425713 | 0.76 | MAOB (0.55) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL5418713 | 0.76 | ROCK2 (0.58) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL27836079 | 0.76 | MAOB (0.58) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL28443718 | 0.75 | CTNNB1 (0.51) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL28443719 | 0.75 | CTNNB1 (0.51) | CTNNB1WNT3AMAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012095781-A1 | INDAZOLE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | PFIZER LIMITED (GB) | 2012-07-19 | — | — | WO | disclosed |
| WO-2012095781-A1 | INDAZOLE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | PFIZER LIMITED (GB) | 2012-07-19 | — | — | WO | disclosed |