Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.64 |
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | HRH1 | P35367 | 3/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291944 | 0.89 | TAAR1 (0.53) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL1979887 | 0.87 | SLC6A4 (0.65) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL1982475 | 0.84 | TAAR1 (0.48) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL16301227 | 0.84 | SLC6A2 (0.55) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL9129451 | 0.82 | SLC6A3 (0.53) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL23783575 | 0.80 | TAAR1 (0.95) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| Phenpromethamine SCHEMBL3958676 | 0.80 | TAAR1 (0.95) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| Phenpromethamine SCHEMBL681384 | 0.80 | TAAR1 (0.95) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| Phenpromethamine SCHEMBL4917327 | 0.80 | TAAR1 (0.95) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL23609196 | 0.78 | TAAR1 (0.57) | TAAR1HTR2AHRH1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498695-B1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID | ZHEJIANG YONGTAI TECHNOLOGY CO LTD (CN) | 2020-12-09 | — | — | EP | claimed |
| US-10556868-B2 | Method for synthesizing 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid and intermediates thereof | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2020-02-11 | — | — | US | claimed |
| US-20190202791-A1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID AND INTERMEDIATES THEREOF | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2019-07-04 | — | — | US | claimed |
| EP-3498695-A1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID, AND INTERMEDIATES THEREOF | Zhejiang Yongtai Technology Co., Ltd. (CN) | 2019-06-19 | — | — | EP | claimed |
| CN-1510030-A | Preparations of 3-(methylthio) propylaldehyde and 2-hydroxy-4-(methylthio) propyl cyanides | 诺沃斯国际公司 | 2004-07-07 | — | — | CN | claimed |
| CN-1092184-C | Process for preparing 3- (methylthio) propanal | NOVAS INTERNAT INC (US) | 2002-10-09 | — | — | CN | claimed |
| CN-1189818-A | Process for the preparation of 3- (methylthio) propanal and 2-hydroxy-4- (methylthio) butanenitrile | NOVAS INTERNATIONAL INC (US) | 1998-08-05 | — | — | CN | claimed |
| WO-2023101556-A1 | NOVEL INHIBITORS OF ASPARTATE TRANSCARBAMOYLASE (ATCASE) AND COMPOSITIONS, METHODS AND USES RELATED THERETO. | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2023-06-08 | — | — | WO | disclosed |
| CN-114040947-B | Cationic electrodeposition coating composition | 日涂汽车涂料有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-114040947-A | Cationic electrodeposition coating composition | 日涂汽车涂料有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-113840884-A | Method for preparing cationic electrodeposition coating composition | 日涂汽车涂料有限公司 | 2021-12-24 | — | — | CN | disclosed |
| EP-3498695-B1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID | ZHEJIANG YONGTAI TECHNOLOGY CO LTD (CN) | 2020-12-09 | — | — | EP | disclosed |
| CN-107969133-B | Cationic electrodeposition coating composition | 日涂汽车涂料有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-1189818-A | Process for the preparation of 3- (methylthio) propanal and 2-hydroxy-4- (methylthio) butanenitrile | NOVAS INTERNATIONAL INC (US) | 1998-08-05 | — | — | CN | disclosed |
| WO-1997041846-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5225411-A | Triazines | ADIR ET COMPAGNIE (FR) | 1993-07-06 | — | — | US | disclosed |
| EP-0333938-B1 | 2-HYDROXY-3-ARYLOXY-PROPYLAMINE DERIVATIVES HAVING CARDIOVASCULAR ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1993-04-14 | — | — | EP | disclosed |
| US-5047425-A | Amine derivatives having cardiovascular activity | SIMES SOCIETA ITALIANA MEDICINALI & SINTETICI SPA (IT) | 1991-09-10 | — | — | US | disclosed |
| EP-0333938-A1 | 2-Hydroxy-3-aryloxy-propylamine derivatives having cardiovascular activity | ZAMBON GROUP S.p.A. (IT) | 1989-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190202791-A1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID AND INTERMEDIATES THEREOF | AFF4, AFF1, AFF2 | TAAR1 1051/4885HTR2A 3623/4885HRH1 179/4885 |
| US-10556868-B2 | Method for synthesizing 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid and intermediates thereof | AFF1, AFF4, AFF2 | TAAR1 1044/4885HTR2A 3501/4885HRH1 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.