Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 4/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384454 | 0.89 | EGLN1 (0.65) | ALDH1A1SMN1; SMN2GSK3BEGLN1MEN1 | |
| SCHEMBL15966805 | 0.86 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2GSK3BEGLN1GAA | |
| SCHEMBL1685954 | 0.80 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL19086572 | 0.80 | RXFP1 (0.46) | ALDH1A1SMN1; SMN2GSK3BMEN1KMT2A | |
| SCHEMBL19086540 | 0.79 | HIF1A (0.45) | ALDH1A1SMN1; SMN2EGLN1MEN1KMT2A | |
| SCHEMBL19086664 | 0.79 | HIF1A (0.71) | ALDH1A1GAAKDM4EHIF1A | |
| SCHEMBL12254381 | 0.79 | EGLN1 (0.68) | GSK3BEGLN1MEN1KMT2AGAA | |
| SCHEMBL2385165 | 0.79 | EGLN1 (0.83) | GSK3BEGLN1HIF1A | |
| SCHEMBL15154302 | 0.79 | EGFR (0.69) | ALDH1A1SMN1; SMN2GSK3BEGLN1MEN1 | |
| SCHEMBL18548898 | 0.78 | MAPT (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190104-B1 | QUINOLINONE COMPOUND AND USE THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-10-27 | — | — | EP | disclosed |
| US-10065928-B2 | Quinolinone compound and use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-09-04 | — | — | US | disclosed |
| US-20170247332-A1 | QUINOLINONE COMPOUND AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-08-31 | — | — | US | disclosed |
| EP-3190104-A1 | QUINOLINONE COMPOUND AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247332-A1 | QUINOLINONE COMPOUND AND USE THEREOF | HIF1AN, HIF1A, EGLN2 | ALDH1A1 517/4885SMN1; SMN2 3132/4885GSK3B 1188/4885 |
| US-10065928-B2 | Quinolinone compound and use thereof | HIF1AN, HIF1A, EGLN2 | ALDH1A1 517/4885SMN1; SMN2 3132/4885GSK3B 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.