Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440017 | 0.76 | KMT2A (0.66) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL3440018 | 0.76 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL3440030 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL17459014 | 0.75 | CYP19A1 (0.44) | ALDH1A1KMT2ACYP19A1MAPTSMN1; SMN2 | |
| SCHEMBL30047373 | 0.74 | CYP19A1 (0.58) | ALDH1A1CYP19A1MAPTSMN1; SMN2CREBBP | |
| SCHEMBL3440019 | 0.72 | ALDH1A1 (0.65) | ALDH1A1KMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL17316446 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1860902 | 0.71 | CYP19A1 (0.55) | ALDH1A1KMT2AMEN1CYP19A1L3MBTL1 | |
| SCHEMBL5468690 | 0.71 | CYP19A1 (0.50) | ALDH1A1KMT2ACYP19A1MAPTSMN1; SMN2 | |
| SCHEMBL19223001 | 0.71 | CYP19A1 (0.47) | ALDH1A1KMT2ACYP19A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |