Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229945 | 0.81 | TRPV4 (0.60) | TRPV4GRM5 | |
| SCHEMBL25012019 | 0.77 | TRPV4 (0.40) | TRPV4GRM5TRPA1 | |
| SCHEMBL17586504 | 0.77 | TRPV4 (0.40) | TRPV4GRM5TRPA1L3MBTL1 | |
| SCHEMBL29649716 | 0.77 | TRPV4 (0.40) | TRPV4GRM5TRPA1L3MBTL1 | |
| SCHEMBL21994683 | 0.76 | TRPV4 (0.39) | TRPV4TRPA1L3MBTL1 | |
| SCHEMBL4729458 | 0.74 | TRPV4 (0.37) | TRPV4GRM5 | |
| SCHEMBL17583207 | 0.72 | KDM5B (0.36) | TRPV4GRM5TRPA1 | |
| SCHEMBL20270776 | 0.72 | TRPV4 (0.36) | TRPV4GRM5 | |
| SCHEMBL18463843 | 0.71 | TRPV4 (0.34) | TRPV4GRM5 | |
| SCHEMBL22601464 | 0.71 | TRPV4 (0.39) | TRPV4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |