SCHEMBL19087050

SCHEMBL19087050

CC(=C\C=C(/C)n1c2ccccc2c2ccccc21)/C(C)=C/C=C(\C)n1c2ccccc2c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
GPR3 P46089 1/20 0.41
LMNA P02545 4/20 0.41
MAPT P10636 4/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 2/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
HSD17B10 Q99714 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NPC1 O15118 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18820625 0.81 POLB (0.59) POLBGPR3LMNAMAPTHTT
SCHEMBL280220 0.81 POLB (0.59) POLBGPR3LMNAMAPTHTT
SCHEMBL24841200 0.81 POLB (0.50) POLBGPR3LMNAMAPTHTT
SCHEMBL21415942 0.78 POLB (0.47) POLBGPR3LMNAMAPTHTT
SCHEMBL20460060 0.78 MAPT (0.55) POLBLMNAMAPTHTTKDM4E
SCHEMBL19823537 0.78 POLB (0.43) POLBGPR3LMNAMAPTHTT
SCHEMBL19563057 0.75 POLB (0.44) POLBGPR3LMNAMAPTHTT
SCHEMBL22363965 0.73 POLB (0.42) POLBGPR3LMNAMAPTHTT
SCHEMBL20040500 0.71 LMNA (0.41) POLBLMNAMAPTHTTKDM4E
SCHEMBL17861171 0.71 POLB (0.47) POLBGPR3LMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220216422-A1 Electroluminescent Device UDC IRELAND LTD (IE) 2022-07-07 US disclosed
US-9923148-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2018-03-20 US disclosed
US-20170194568-A9 Electroluminescent Device UDC IRELAND LIMITED (IE) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216422-A1 Electroluminescent Device PNPO, ODC1, AXL POLB 1648/4885GPR3 3811/4885LMNA 4324/4885
US-20170194568-A9 Electroluminescent Device DPYD, PNPO, TYMP POLB 796/4885GPR3 4154/4885LMNA 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.