Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19078467 | 0.90 | MAPT (0.43) | MAPTCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL19087942 | 0.74 | MAPT (0.42) | MAPTTP53HTTTDP1ALDH1A1 | |
| SCHEMBL19087988 | 0.72 | ENPP2 (0.44) | MAPTCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL12643869 | 0.72 | MAPT (0.70) | MAPTCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL19078389 | 0.72 | FFAR4 (0.51) | MAPTCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL19078469 | 0.72 | MAPT (0.48) | MAPTCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL19088118 | 0.71 | KDM4E (0.43) | MAPTCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL17305251 | 0.71 | MAPT (0.45) | MAPTCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL19078440 | 0.71 | MAPT (0.42) | MAPTTP53HTTTDP1ALDH1A1 | |
| SCHEMBL19078394 | 0.70 | FFAR4 (0.56) | MAPTCYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190697-A1 | NOVEL PYRROLIDINE COMPOUND AND APPLICATION AS MELANOCORTIN RECEPTOR AGONIST | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190697-A1 | NOVEL PYRROLIDINE COMPOUND AND APPLICATION AS MELANOCORTIN RECEPTOR AGONIST | MC1R, MC5R, MC3R | MAPT 3317/4885CYP2C9 1840/4885CYP2C19 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.