Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FABP7 | O15540 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019836 | 0.79 | GSTP1 (0.48) | L3MBTL1KMT2ACYP2C19 | |
| SCHEMBL21159519 | 0.76 | BRD4 (0.41) | BRD4LTA4HFABP7MEN1KMT2A | |
| SCHEMBL28716976 | 0.76 | TSHR (0.54) | L3MBTL1TDP1TSHRLTA4HNAAA | |
| SCHEMBL23258791 | 0.74 | ATM (0.41) | L3MBTL1BRD4ATMFABP7PIK3CD | |
| SCHEMBL18857842 | 0.74 | MAPK14 (0.47) | ATMFABP7PIK3CDPIK3CAPIK3CB | |
| SCHEMBL1066576 | 0.73 | TSHR (0.67) | L3MBTL1TDP1TSHRLTA4HNAAA | |
| SCHEMBL18256350 | 0.73 | LTA4H (0.40) | L3MBTL1BRD4TSHRLTA4HATM | |
| SCHEMBL23279538 | 0.73 | LTA4H (0.40) | L3MBTL1BRD4TSHRLTA4HATM | |
| SCHEMBL9214604 | 0.72 | FABP7 (0.51) | BRD4ATMFABP7PIK3CDPIK3CA | |
| SCHEMBL18248132 | 0.72 | PRMT5 (0.39) | BRD4ATMFABP7PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116702-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2017-07-06 | — | — | WO | disclosed |