Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089224 | 0.93 | PDE4D (0.33) | PDE4D | |
| SCHEMBL19089231 | 0.92 | PDE4D (0.34) | PDE4D | |
| SCHEMBL19089417 | 0.92 | ROCK1 (0.32) | ROCK2ROCK1 | |
| SCHEMBL19084260 | 0.90 | NPC1 (0.31) | — | |
| SCHEMBL19091285 | 0.89 | PDE4D (0.31) | PDE4D | |
| SCHEMBL17427102 | 0.89 | PDE4D (0.33) | PDE4D | |
| SCHEMBL19091277 | 0.88 | ROCK1 (0.32) | ROCK2ROCK1 | |
| SCHEMBL19089226 | 0.88 | RIPK1 (0.35) | PDE4DROCK2ROCK1 | |
| SCHEMBL17898779 | 0.88 | — | — | |
| SCHEMBL19091275 | 0.88 | FGFR4 (0.30) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116949-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |