Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.45 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35210275 | 0.92 | EGFR (0.55) | EGFRFGFR1ERBB3DUS2 | |
| SCHEMBL19089518 | 0.92 | EGFR (0.55) | EGFRFGFR1ERBB3DUS2 | |
| SCHEMBL35210302 | 0.84 | EGFR (0.58) | EGFRERBB3DUS2 | |
| SCHEMBL19089514 | 0.84 | EGFR (0.58) | EGFRERBB3DUS2 | |
| SCHEMBL35210310 | 0.83 | EGFR (0.57) | EGFRERBB3DUS2 | |
| SCHEMBL20548791 | 0.83 | EGFR (0.57) | EGFRERBB3DUS2 | |
| SCHEMBL20655477 | 0.81 | EGFR (0.57) | EGFRERBB3DUS2 | |
| SCHEMBL19089507 | 0.80 | EGFR (0.52) | EGFRFGFR1FGFR4ERBB3DUS2 | |
| SCHEMBL35210297 | 0.80 | EGFR (0.52) | EGFRFGFR1FGFR4ERBB3DUS2 | |
| SCHEMBL19089508 | 0.78 | EGFR (0.58) | EGFRCTSCERBB3DUS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |