SCHEMBL35210310

SCHEMBL35210310

C=CC(=O)Nc1cc(Nc2cc(Nc3ccc(F)c(Cl)c3)ncn2)c(OC)cc1N1CCCCC1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 19/20 0.57
ERBB3 P21860 1/20 0.57
DUS2 Q9NX74 1/20 0.57
ERBB2 P04626 5/20 0.51
ERBB4 Q15303 3/20 0.51
GAK O14976 1/20 0.51
RIPK2 O43353 1/20 0.51
NR1I2 O75469 1/20 0.51
LCK P06239 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
CHRM1 P11229 1/20 0.51
SRC P12931 1/20 0.51
DRD2 P14416 1/20 0.51
ADRA2C P18825 1/20 0.51
SLC6A2 P23975 1/20 0.51
MC3R P41968 1/20 0.51
JAK3 P52333 1/20 0.51
SLC6A3 Q01959 1/20 0.51
PDE4D Q08499 1/20 0.51
KCNH2 Q12809 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20548791 1.00 EGFR (0.57) EGFRERBB3DUS2ERBB2ERBB4
SCHEMBL20655477 0.93 EGFR (0.57) EGFRERBB3DUS2JAK3KCNH2
SCHEMBL19089514 0.93 EGFR (0.58) EGFRERBB3DUS2ERBB2JAK3
SCHEMBL35210302 0.93 EGFR (0.58) EGFRERBB3DUS2ERBB2JAK3
SCHEMBL19089518 0.92 EGFR (0.55) EGFRERBB3DUS2ERBB2
SCHEMBL35210275 0.92 EGFR (0.55) EGFRERBB3DUS2ERBB2
SCHEMBL35210297 0.88 EGFR (0.52) EGFRERBB3DUS2KCNH2
SCHEMBL19089507 0.88 EGFR (0.52) EGFRERBB3DUS2KCNH2
SCHEMBL19089508 0.88 EGFR (0.58) EGFRERBB3DUS2ERBB2ERBB4
SCHEMBL35210274 0.88 EGFR (0.58) EGFRERBB3DUS2ERBB2ERBB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP claimed
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP disclosed