Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.66 |
| ▸ | IGF1R | P08069 | 4/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089325 | 0.94 | EGFR (0.65) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089549 | 0.92 | EGFR (0.63) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089336 | 0.92 | EGFR (0.76) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089547 | 0.91 | EGFR (0.62) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089553 | 0.91 | EGFR (0.72) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089550 | 0.90 | EGFR (0.67) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089560 | 0.89 | EGFR (0.52) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089328 | 0.89 | EGFR (0.65) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL20548842 | 0.88 | EGFR (0.66) | EGFRIGF1RKCNH2 | |
| SCHEMBL19089558 | 0.87 | EGFR (0.60) | EGFRIGF1RKCNH2CDK2DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |