Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.52 |
| ▸ | IGF1R | P08069 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.46 |
| ▸ | PIP4K2A | P48426 | 3/20 | 0.42 |
| ▸ | PIP4K2B | P78356 | 3/20 | 0.42 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.41 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.41 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CCNH | P51946 | 1/20 | 0.37 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089563 | 0.90 | IGF1R (0.53) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089554 | 0.89 | EGFR (0.66) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089559 | 0.87 | EGFR (0.48) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089325 | 0.83 | EGFR (0.65) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089549 | 0.82 | EGFR (0.63) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089336 | 0.81 | EGFR (0.76) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089547 | 0.81 | EGFR (0.62) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089553 | 0.80 | EGFR (0.72) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL19089550 | 0.79 | EGFR (0.67) | EGFRIGF1RKCNH2CDK2DYRK1B | |
| SCHEMBL20656036 | 0.78 | EGFR (0.61) | EGFRKCNH2CDK2DYRK1BPIP4K2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |