Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 12/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089573 | 0.94 | EGFR (0.45) | CDK4CDK2EGFRLCKKDR | |
| SCHEMBL19089575 | 0.84 | EGFR (0.41) | CDK4CDK2EGFRKDRERBB3 | |
| SCHEMBL20548850 | 0.83 | EGFR (0.66) | EGFR | |
| SCHEMBL35210261 | 0.83 | EGFR (0.66) | EGFR | |
| SCHEMBL19089675 | 0.82 | EGFR (0.49) | EGFRKDRTEKERBB3 | |
| SCHEMBL19089671 | 0.79 | EGFR (0.46) | EGFR | |
| SCHEMBL19089341 | 0.78 | EGFR (0.41) | CDK4CDK2EGFRERBB3 | |
| SCHEMBL22507913 | 0.77 | EGFR (0.49) | EGFRBRAF | |
| SCHEMBL20548889 | 0.76 | EGFR (0.68) | EGFR | |
| SCHEMBL35210258 | 0.76 | EGFR (0.68) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |