Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.41 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.41 |
| ▸ | CDK4 | P11802 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089573 | 0.86 | EGFR (0.45) | EGFRERBB3CDK4CDK2KDR | |
| SCHEMBL19089567 | 0.84 | CDK4 (0.49) | EGFRERBB3CDK4CDK2KDR | |
| SCHEMBL35210263 | 0.84 | EGFR (0.61) | EGFR | |
| SCHEMBL20548764 | 0.84 | EGFR (0.61) | EGFR | |
| SCHEMBL19089341 | 0.78 | EGFR (0.41) | EGFRERBB3CDK4CDK2MEN1 | |
| SCHEMBL19089675 | 0.78 | EGFR (0.49) | EGFRERBB3SRCKDR | |
| SCHEMBL35210281 | 0.78 | EGFR (0.46) | EGFRERBB3SRCKDR | |
| SCHEMBL19089500 | 0.78 | EGFR (0.46) | EGFRERBB3SRCKDR | |
| SCHEMBL19089633 | 0.77 | EGFR (0.39) | EGFRERBB3CDK4CDK2MEN1 | |
| SCHEMBL19089566 | 0.76 | EGFR (0.51) | EGFRERBB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |