SCHEMBL19089633 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	EGFR	P00533	9/20	0.39

▸	ERBB3	P21860	3/20	0.38

▸	TNNI3K	Q59H18	2/20	0.38

▸	EPHB4	P54760	1/20	0.38

▸	CDK4	P11802	4/20	0.37

▸	CDK2	P24941	4/20	0.37

▸	CCNE1	P24864	1/20	0.36

▸	MEN1	O00255	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

▸	CYP3A4	P08684	1/20	0.35

▸	FGFR3	P22607	1/20	0.35

▸	CYP2C19	P33261	1/20	0.35

▸	ACHE	P22303	1/20	0.35

▸	ERBB2	P04626	1/20	0.35

▸	PIP4K2A	P48426	1/20	0.35

▸	FGFR1	P11362	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19089675	0.88	EGFR (0.49)	EGFRERBB3EPHB4ERBB2
SCHEMBL19089425	0.86	CDK4 (0.40)	EGFRERBB3TNNI3KCDK4CDK2
SCHEMBL35210348	0.86	CDK4 (0.40)	EGFRERBB3TNNI3KCDK4CDK2
SCHEMBL19089359	0.84	EGFR (0.36)	EGFRERBB3TNNI3KEPHB4CDK4
SCHEMBL19089627	0.84	EPHA2 (0.39)	EGFRERBB3EPHB4ERBB2PIP4K2A
SCHEMBL19089564	0.83	EGFR (0.59)	EGFRERBB2
SCHEMBL19089361	0.82	EPHA2 (0.48)	EGFREPHB4ERBB2
SCHEMBL19089356	0.82	EGFR (0.39)	EGFRERBB3TNNI3KCDK4CDK2
SCHEMBL19089358	0.82	EGFR (0.39)	EGFRERBB3TNNI3KCDK4CDK2
SCHEMBL19089341	0.82	EGFR (0.41)	EGFRERBB3EPHB4CDK4CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017114500-A1	ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY	恩瑞生物医药科技（上海）有限公司	2017-07-06	—	—	WO	disclosed