SCHEMBL19089627 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	EPHA2	P29317	5/20	0.39

▸	KDR	P35968	5/20	0.39

▸	EPHB4	P54760	3/20	0.39

▸	ERBB2	P04626	3/20	0.39

▸	EGFR	P00533	10/20	0.36

▸	IDH1	O75874	1/20	0.36

▸	CNR2	P34972	1/20	0.35

▸	PIP4K2A	P48426	1/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	IKBKE	Q14164	1/20	0.34

▸	TBK1	Q9UHD2	1/20	0.34

▸	ERBB3	P21860	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19089361	0.88	EPHA2 (0.48)	EPHA2KDREPHB4ERBB2EGFR
SCHEMBL19089359	0.85	EGFR (0.36)	EPHB4ERBB2EGFRPIP4K2AERBB3
SCHEMBL35210260	0.85	EGFR (0.52)	EGFR
SCHEMBL20548935	0.85	EGFR (0.52)	EGFR
SCHEMBL20656019	0.85	EGFR (0.39)	ERBB2EGFR
SCHEMBL19089633	0.84	EGFR (0.39)	EPHB4ERBB2EGFRPIP4K2AERBB3
SCHEMBL19089675	0.82	EGFR (0.49)	KDREPHB4ERBB2EGFRERBB3
SCHEMBL19089356	0.79	EGFR (0.39)	EGFRIKBKETBK1ERBB3
SCHEMBL19089568	0.78	INSR (0.43)	EPHA2KDREPHB4ERBB2EGFR
SCHEMBL19089341	0.77	EGFR (0.41)	EPHB4EGFRERBB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017114500-A1	ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY	恩瑞生物医药科技（上海）有限公司	2017-07-06	—	—	WO	disclosed