Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.45 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.45 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089423 | 0.89 | EGFR (0.44) | EGFRERBB2AURKAINSRFBP1 | |
| SCHEMBL20548944 | 0.88 | EGFR (0.43) | EGFRERBB2AURKAINSRFBP1 | |
| SCHEMBL19089668 | 0.86 | EGFR (0.54) | EGFRKDR | |
| SCHEMBL19089424 | 0.84 | KMT2A (0.43) | EGFRTNNI3KERBB3 | |
| SCHEMBL19089505 | 0.83 | EGFR (0.56) | EGFRERBB2FBP1KDRTNNI3K | |
| SCHEMBL7777464 | 0.79 | EGFR (0.61) | EGFRERBB2AURKAINSRFBP1 | |
| SCHEMBL31588399 | 0.78 | SCN9A (0.43) | — | |
| SCHEMBL2203223 | 0.78 | EGFR (0.55) | EGFRERBB2AURKAINSRFBP1 | |
| SCHEMBL2205173 | 0.77 | KMT2A (0.55) | EGFRERBB2TNNI3K | |
| SCHEMBL28056977 | 0.76 | EGFR (0.55) | EGFRERBB2AURKAINSRFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |