SCHEMBL19089864

SCHEMBL19089864

C=Cc1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccc(C45CC6CC(CC(C6)C4)C5)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
LMNA P02545 3/20 0.40
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
GAA P10253 2/20 0.37
HSD11B1 P28845 1/20 0.36
CNR1 P21554 2/20 0.35
CNR2 P34972 2/20 0.35
EPHX2 P34913 2/20 0.35
HTT P42858 2/20 0.35
RARB P10826 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 1/20 0.34
GFER P55789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19089853 0.95 LMNA (0.44) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL21039042 0.89 LMNA (0.49) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL19089802 0.89 LMNA (0.49) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL23691172 0.89 LMNA (0.49) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL23691253 0.89 LMNA (0.49) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL24421734 0.89 LMNA (0.49) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL19089833 0.89 LMNA (0.49) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL24422010 0.87 LMNA (0.47) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL24421717 0.87 LMNA (0.47) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL22815321 0.87 LMNA (0.47) ALDH1A1LMNAGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017116168-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 머티어리얼사이언스 주식회사 2017-07-06 WO disclosed