SCHEMBL19089867

SCHEMBL19089867

C#Cc1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccc(C45CC6CC(CC(C6)C4)C5)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 7/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 2/20 0.40
HSD11B1 P28845 1/20 0.36
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
EPHX2 P34913 1/20 0.35
HTT P42858 1/20 0.35
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
GFER P55789 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21039042 0.89 LMNA (0.49) PGRALDH1A1LMNAHSD11B1GRIN2D
SCHEMBL24421734 0.89 LMNA (0.49) PGRALDH1A1LMNAHSD11B1GRIN2D
SCHEMBL19089802 0.89 LMNA (0.49) PGRALDH1A1LMNAHSD11B1GRIN2D
SCHEMBL23691253 0.89 LMNA (0.49) PGRALDH1A1LMNAHSD11B1GRIN2D
SCHEMBL19089833 0.89 LMNA (0.49) PGRALDH1A1LMNAHSD11B1GRIN2D
SCHEMBL23691172 0.89 LMNA (0.49) PGRALDH1A1LMNAHSD11B1GRIN2D
SCHEMBL24422008 0.87 LMNA (0.47) PGRALDH1A1LMNAHSD11B1GRIN2D
SCHEMBL24422018 0.87 LMNA (0.47) PGRALDH1A1LMNAHSD11B1GRIN2D
SCHEMBL22815321 0.87 LMNA (0.47) PGRALDH1A1LMNAHSD11B1GRIN2D
SCHEMBL24422010 0.87 LMNA (0.47) PGRALDH1A1LMNAHSD11B1GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017116168-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 머티어리얼사이언스 주식회사 2017-07-06 WO disclosed