Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091224 | 0.87 | MAPT (0.41) | MAPTHRH3 | |
| SCHEMBL26205508 | 0.82 | HRH3 (0.36) | MAPTHRH3 | |
| SCHEMBL26727305 | 0.82 | HRH3 (0.36) | MAPTHRH3 | |
| SCHEMBL26205503 | 0.82 | HRH3 (0.36) | MAPTHRH3 | |
| SCHEMBL23325006 | 0.79 | ACKR3 (0.32) | — | |
| SCHEMBL20988332 | 0.79 | KDM4E (0.33) | HRH3 | |
| SCHEMBL12026533 | 0.77 | CHRNA7 (0.32) | — | |
| SCHEMBL15598914 | 0.77 | CHRNA7 (0.32) | — | |
| SCHEMBL15981398 | 0.77 | CHRNA7 (0.32) | — | |
| SCHEMBL9005055 | 0.77 | CHRNA7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246478-B2 | Polyene macrolide derivative | SHIONOGI & CO., LTD. (JP) | 2019-04-02 | — | — | US | disclosed |
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | ERG28, RPL23, RPL10 | MAPT 2901/4885HRH3 2698/4885 |
| US-10246478-B2 | Polyene macrolide derivative | ERG28, RPL23, RPL10 | MAPT 2901/4885HRH3 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.