Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9108324 | 1.00 | ATM (0.53) | ATMPIK3CDMAPTDPP4DPP8 | |
| SCHEMBL22853605 | 1.00 | ATM (0.53) | ATMPIK3CDMAPTDPP4DPP8 | |
| SCHEMBL9107535 | 1.00 | ATM (0.53) | ATMPIK3CDMAPTDPP4DPP8 | |
| SCHEMBL10105388 | 1.00 | ATM (0.53) | ATMPIK3CDMAPTDPP4DPP8 | |
| SCHEMBL10021563 | 1.00 | ATM (0.53) | ATMPIK3CDMAPTDPP4DPP8 | |
| SCHEMBL14610923 | 0.84 | ATM (0.44) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL11953213 | 0.84 | ATM (0.44) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL16852134 | 0.84 | ATM (0.44) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL10033281 | 0.84 | ATM (0.44) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL26724067 | 0.84 | ATM (0.44) | ATMPIK3CDDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246478-B2 | Polyene macrolide derivative | SHIONOGI & CO., LTD. (JP) | 2019-04-02 | — | — | US | disclosed |
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | ERG28, RPL23, RPL10 | ATM 4287/4885PIK3CD 1860/4885MAPT 2901/4885 |
| US-10246478-B2 | Polyene macrolide derivative | ERG28, RPL23, RPL10 | ATM 4287/4885PIK3CD 1860/4885MAPT 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.