Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27274544 | 0.82 | TSHR (0.61) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL4958389 | 0.82 | TSHR (0.61) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL19091265 | 0.81 | GABRP (0.39) | TSHRALDH1A1LMNACYP1A2 | |
| SCHEMBL16668510 | 0.80 | TSHR (0.58) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL4530697 | 0.80 | TSHR (0.58) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL28305335 | 0.80 | TSHR (0.64) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8863084 | 0.79 | HSD17B10 (0.40) | TSHRALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4060095 | 0.79 | TSHR (0.67) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL17883542 | 0.79 | TSHR (0.56) | TSHRL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL15216418 | 0.79 | TSHR (0.56) | TSHRL3MBTL1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116954-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |