SCHEMBL190954

SCHEMBL190954

c1ccc(-c2ccnc(-c3ccccc3)n2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.63
HSP90AA1 P07900 1/20 0.63
PRKACA P17612 1/20 0.63
ADORA2A P29274 1/20 0.63
KMT2A Q03164 10/20 0.60
MEN1 O00255 9/20 0.60
MAPT P10636 5/20 0.60
KDM4E B2RXH2 3/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
GABRA1 P14867 1/20 0.60
GABRG2 P18507 1/20 0.60
GABRB3 P28472 1/20 0.60
GABRA5 P31644 1/20 0.60
GABRA3 P34903 1/20 0.60
NPC1 O15118 5/20 0.57
RAB9A P51151 4/20 0.57
POLB P06746 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
PTK2B Q14289 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29620532 1.00 AURKA (0.63) AURKAHSP90AA1PRKACAADORA2AKMT2A
Ammonia Solution, Strong SCHEMBL20267253 0.98 AURKA (0.61) AURKAHSP90AA1PRKACAADORA2AKMT2A
SCHEMBL29730468 0.96 KMT2A (0.61) AURKAHSP90AA1PRKACAADORA2AKMT2A
SCHEMBL18731741 0.96 KMT2A (0.61) AURKAHSP90AA1PRKACAADORA2AKMT2A
Ethylene SCHEMBL28961184 0.96 AURKA (0.59) AURKAHSP90AA1PRKACAADORA2AKMT2A
SCHEMBL21003801 0.96 KMT2A (0.61) AURKAHSP90AA1PRKACAADORA2AKMT2A
SCHEMBL18732403 0.96 KMT2A (0.61) AURKAHSP90AA1PRKACAADORA2AKMT2A
SCHEMBL18212429 0.94 KMT2A (0.59) AURKAHSP90AA1PRKACAADORA2AKMT2A
Triphenylene SCHEMBL29177804 0.94 AURKA (0.57) AURKAHSP90AA1PRKACAADORA2AKMT2A
SCHEMBL18905473 0.92 GABRA1 (0.71) AURKAHSP90AA1PRKACAADORA2AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 729 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425735-B 2, 4-Diphenylamine pyrimidine derivative, and preparation method and application thereof 中南大学 2025-06-17 CN claimed
CN-118480146-A Preparation method of polyprenol-based light-controlled antibacterial synergist 中国林业科学研究院林产化学工业研究所 2024-08-13 CN claimed
CN-113871540-B Organic electroluminescent device and application thereof 江苏三月科技股份有限公司 2024-04-19 CN claimed
CN-111559981-B Biphenyl-pyrimidine conjugate and preparation method and application thereof 杭州庆正鸿科技有限公司 2023-08-01 CN claimed
CN-115745895-A Structure and synthetic route of ultraviolet absorbent diphenyl pyrimidine ethylene 温州奥洋科技有限公司 2023-03-07 CN claimed
CN-111454235-B Organic electroluminescent materials and devices 机光科技股份有限公司 2022-08-12 CN claimed
CN-114105954-A Compound and application thereof 上海和辉光电股份有限公司 2022-03-01 CN claimed
CN-111187225-B Condensed ring aromatic hydrocarbon derivative with quinoxaline group and application thereof 北京鼎材科技有限公司 2021-06-11 CN claimed
CN-110195278-B Preparation process and application of ultra-high-count PI-PSA electrospun fiber long yarn 江西先材纳米纤维科技有限公司 2021-04-06 CN claimed
CN-110205726-B Preparation process of electro-spun carbon-doped polyimide conductive nanofiber long yarn 江西先材纳米纤维科技有限公司 2020-09-29 CN claimed
US-5194972-A Microwave phase modulation with liquid crystals HUGHES AIRCRAFT COMPANY (US) 1993-03-16 US claimed
US-5167855-A Electrooptics and display devices UNIVERSITY RESEARCH CORPORATION (US) 1992-12-01 US claimed
EP-0293763-B1 SMECTIC LIQUID CRYSTAL MIXTURE CHISSO CORPORATION (JP) 1992-07-29 EP claimed
US-5130048-A Enantiomorphs for optical apparatus DISPLAYTECH, INC. (US) 1992-07-14 US claimed
EP-0472403-A2 Microwave phase modulation with liquid crystals Hughes Aircraft Company (US) 1992-02-26 EP claimed
WO-1992001765-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITIONS CONTAINING CHIRAL HALOALKOXY TAIL UNITS DISPLAYTECH, INC. (US) 1992-02-06 WO claimed
WO-1992001763-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITIONS CONTAINING CHIRAL HALOALKOXY TAIL UNITS DISPLAYTECH, INC. (US) 1992-02-06 WO claimed
WO-1992001766-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITIONS CONTAINING HALOGENATED CORES AND CHIRAL HALOALKOXY TAIL UNITS DISPLAYTECH, INC. (US) 1992-02-06 WO claimed
US-4882083-A CONTAINING OPTICALLY ACTIVE COMPOUND; HIGH SPEED RESPONSE DISPLAY ELEMENT CHISSO CORPORATION (JP) 1989-11-21 US claimed
EP-0293763-A2 Smectic liquid crystal mixture CHISSO CORPORATION (JP) 1988-12-07 EP claimed