Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.73 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.73 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.73 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920719 | 0.93 | MEN1 (0.71) | MEN1KMT2ACYP2C9ABCC3ABCC4 | |
| SCHEMBL8207626 | 0.92 | MEN1 (0.70) | MEN1KMT2ACYP2C9ABCC3ABCC4 | |
| SCHEMBL14521888 | 0.91 | KMT2A (0.69) | MEN1KMT2ACYP2C9ABCC3ABCC4 | |
| SCHEMBL20920718 | 0.91 | CYP2C9 (0.75) | MEN1KMT2ACYP2C9ABCC3ABCC4 | |
| SCHEMBL11198683 | 0.88 | CYP2C9 (0.71) | MEN1KMT2ACYP2C9ABCC3ABCC4 | |
| SCHEMBL28623676 | 0.87 | KMT2A (0.64) | MEN1KMT2ACYP2C9ABCC3ABCC4 | |
| SCHEMBL14371709 | 0.87 | MEN1 (0.64) | MEN1KMT2ACYP2C9ABCC3ABCC4 | |
| SCHEMBL14544499 | 0.86 | MEN1 (0.63) | MEN1KMT2ACYP2C9ABCC3ABCC4 | |
| SCHEMBL21362689 | 0.86 | MEN1 (0.60) | MEN1KMT2ACYP2C9ABCC3ABCC4 | |
| SCHEMBL28605437 | 0.85 | KMT2A (0.62) | MEN1KMT2ACYP2C9ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170199166-A1 | METHODS FOR DETERMINING RELATIVE RESPONSE FACTORS FOR IMPURITY ANALYSIS USING LIQUID CHROMATOGRAPHY WITH ABSORBANCE AND EVAPORATIVE LIGHT SCATTERING DETECTION | WATERS TECHNOLOGIES CORPORATION (US) | 2017-07-13 | — | — | US | disclosed |