Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.71 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19096540 | 0.93 | MEN1 (0.73) | MEN1ABCC3ABCC4ABCB11CYP2C9 | |
| SCHEMBL8207626 | 0.91 | MEN1 (0.70) | MEN1ABCC3ABCC4ABCB11CYP2C9 | |
| SCHEMBL20920718 | 0.90 | CYP2C9 (0.75) | MEN1ABCC3ABCC4ABCB11CYP2C9 | |
| SCHEMBL14521888 | 0.90 | KMT2A (0.69) | MEN1ABCC3ABCC4ABCB11CYP2C9 | |
| SCHEMBL11198683 | 0.88 | CYP2C9 (0.71) | MEN1ABCC3ABCC4ABCB11CYP2C9 | |
| SCHEMBL28623676 | 0.86 | KMT2A (0.64) | MEN1ABCC3ABCC4ABCB11CYP2C9 | |
| SCHEMBL14371709 | 0.86 | MEN1 (0.64) | MEN1ABCC3ABCC4ABCB11CYP2C9 | |
| SCHEMBL14544499 | 0.85 | MEN1 (0.63) | MEN1ABCC3ABCC4ABCB11CYP2C9 | |
| SCHEMBL28605437 | 0.84 | KMT2A (0.62) | MEN1ABCC3ABCC4ABCB11CYP2C9 | |
| SCHEMBL11189249 | 0.84 | CYP2C9 (0.86) | MEN1ABCC3ABCC4ABCB11CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10265692-B2 | Ex vivo methods for predicting and confirming in vivo metabolism of pharmaceutically active compounds | EMPIRIKO CORPORATION (US) | 2019-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10265692-B2 | Ex vivo methods for predicting and confirming in vivo metabolism of pharmaceutically active compounds | CYP3A43, CYP3A4, CYP2D6 | MEN1 2675/4885ABCC3 514/4885ABCC4 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.