Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19098731 | 0.92 | MAPK1 (0.55) | MAPK1MAP3K14 | |
| SCHEMBL19099169 | 0.89 | MAPK1 (0.59) | MAPK1MAP3K14 | |
| SCHEMBL19099029 | 0.88 | MAPK1 (0.58) | MAPK1MAP3K14 | |
| SCHEMBL19098724 | 0.86 | MAP3K14 (0.52) | MAPK1MAP3K14 | |
| SCHEMBL19099027 | 0.86 | MAPK1 (0.58) | MAPK1MAP3K14 | |
| SCHEMBL19099170 | 0.85 | MAP3K14 (0.49) | MAPK1MAP3K14 | |
| SCHEMBL19099165 | 0.80 | MAPK1 (0.82) | MAPK1 | |
| SCHEMBL19099032 | 0.80 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL19099286 | 0.79 | MAPK1 (0.62) | MAPK1MAP3K14 | |
| SCHEMBL19099172 | 0.79 | MAPK1 (0.62) | MAPK1MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922405-B | Compound with ERK kinase inhibitory activity, preparation method and application thereof | 中国科学院上海药物研究所 | 2021-02-19 | — | — | CN | disclosed |
| WO-2017114510-A1 | COMPOUND HAVING ERK KINASE INHIBITORY ACTIVITY, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | 中国科学院上海药物研究所 | 2017-07-06 | — | — | WO | disclosed |