Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.42 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | FGF1 | P05230 | 1/20 | 0.32 |
| ▸ | FGF2 | P09038 | 1/20 | 0.32 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101885 | 0.93 | TMPRSS2 (0.37) | TMPRSS2TDP1 | |
| SCHEMBL16708478 | 0.92 | TMPRSS2 (0.39) | TMPRSS2POLBADORA3TDP1 | |
| SCHEMBL25495980 | 0.88 | TMPRSS2 (0.36) | TMPRSS2LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL16708476 | 0.87 | SMN1; SMN2 (0.35) | TMPRSS2ADORA3TDP1 | |
| SCHEMBL16708474 | 0.86 | TMPRSS2 (0.34) | TMPRSS2TDP1 | |
| SCHEMBL16708473 | 0.85 | TMPRSS2 (0.49) | TMPRSS2LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL19101754 | 0.83 | TMPRSS2 (0.40) | TMPRSS2POLBTDP1 | |
| SCHEMBL16708477 | 0.83 | TMPRSS2 (0.47) | TMPRSS2LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL19101769 | 0.82 | TMPRSS2 (0.34) | TMPRSS2TDP1 | |
| SCHEMBL25496003 | 0.81 | PDE4B (0.33) | TMPRSS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701682-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-07-11 | — | — | US | disclosed |