Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19779071 | 1.00 | POLRMT (0.40) | POLRMTMAP4K4DOT1LSTING1TNK2 | |
| SCHEMBL24942302 | 0.86 | POLRMT (0.39) | POLRMTMAP4K4DOT1LTNIK | |
| SCHEMBL19101755 | 0.84 | POLRMT (0.38) | POLRMTMAP4K4 | |
| SCHEMBL19779074 | 0.84 | POLRMT (0.38) | POLRMTMAP4K4 | |
| SCHEMBL20960069 | 0.81 | — | — | |
| SCHEMBL26229927 | 0.79 | POLRMT (0.41) | POLRMTMAP4K4DOT1LSTING1TNK2 | |
| SCHEMBL25776452 | 0.78 | POLRMT (0.38) | POLRMTMAP4K4DOT1L | |
| SCHEMBL19227690 | 0.78 | POLRMT (0.39) | POLRMTMAP4K4DOT1LSTING1 | |
| SCHEMBL16699309 | 0.77 | POLRMT (0.41) | POLRMTMAP4K4DOT1LSTING1TNK2 | |
| SCHEMBL27438673 | 0.77 | POLRMT (0.41) | POLRMTMAP4K4DOT1LSTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701682-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-07-11 | — | — | US | disclosed |