Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17435762 | 0.93 | KMT2A (0.41) | KMT2AMEN1CYP2C9CYP3A4DHODH | |
| SCHEMBL19102767 | 0.93 | MEN1 (0.43) | KMT2AMEN1CYP2C9CYP3A4DHODH | |
| SCHEMBL15529715 | 0.88 | MEN1 (0.41) | KMT2AMEN1CYP2C9CYP3A4DHODH | |
| SCHEMBL19102763 | 0.87 | MEN1 (0.45) | KMT2AMEN1CYP2C9CYP3A4DHODH | |
| SCHEMBL19102701 | 0.85 | MEN1 (0.41) | KMT2AMEN1CYP2C9CYP3A4DHODH | |
| SCHEMBL19102589 | 0.84 | DHODH (0.40) | KMT2AMEN1CYP2C9CYP3A4DHODH | |
| SCHEMBL17435550 | 0.83 | MEN1 (0.38) | KMT2AMEN1CYP2C9CYP3A4DHODH | |
| SCHEMBL19102841 | 0.82 | MEN1 (0.42) | KMT2AMEN1CYP3A4DHODHALDH1A1 | |
| SCHEMBL17435534 | 0.82 | MEN1 (0.39) | KMT2AMEN1CYP2C9CYP3A4DHODH | |
| SCHEMBL19102772 | 0.82 | MEN1 (0.42) | KMT2AMEN1CYP2C9CYP3A4DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |