Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TACR3 | P29371 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17435731 | 0.94 | MEN1 (0.40) | MEN1KMT2ATACR3HDAC1TP53 | |
| SCHEMBL19102589 | 0.89 | DHODH (0.40) | MEN1KMT2ATACR3HDAC1TP53 | |
| SCHEMBL19102701 | 0.88 | MEN1 (0.41) | MEN1KMT2ATACR3DHODHGAA | |
| SCHEMBL19102772 | 0.85 | MEN1 (0.42) | MEN1KMT2ATACR3TP53DHODH | |
| SCHEMBL17435573 | 0.85 | MEN1 (0.39) | MEN1KMT2ATACR3HDAC1TP53 | |
| SCHEMBL17435505 | 0.84 | DHODH (0.39) | MEN1KMT2ATACR3HDAC1TP53 | |
| SCHEMBL19102767 | 0.83 | MEN1 (0.43) | MEN1KMT2ATACR3DHODHGAA | |
| SCHEMBL17435534 | 0.83 | MEN1 (0.39) | MEN1KMT2ATACR3DHODHGAA | |
| SCHEMBL19102702 | 0.82 | KMT2A (0.42) | MEN1KMT2ATACR3DHODHGAA | |
| SCHEMBL19102763 | 0.82 | MEN1 (0.45) | MEN1KMT2ADHODHGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |