Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | ACACA | Q13085 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19102594 | 0.95 | ALDH1A1 (0.34) | MEN1RAB9AKMT2AACACBACACA | |
| SCHEMBL17435515 | 0.93 | MEN1 (0.33) | MEN1RAB9AKMT2AACACBACACA | |
| SCHEMBL19102695 | 0.87 | KLK7 (0.35) | MEN1RAB9AKMT2AALDH1A1GAA | |
| SCHEMBL17435544 | 0.87 | ALDH1A1 (0.33) | MEN1RAB9AKMT2AACACBALDH1A1 | |
| SCHEMBL17435507 | 0.87 | ACACB (0.36) | MEN1RAB9AKMT2AACACBACACA | |
| SCHEMBL19102843 | 0.87 | ALDH1A1 (0.34) | MEN1RAB9AKMT2AACACBALDH1A1 | |
| SCHEMBL19102703 | 0.82 | ALDH1A1 (0.38) | MEN1RAB9AKMT2AALDH1A1GAA | |
| SCHEMBL19102591 | 0.81 | ALDH1A1 (0.37) | MEN1RAB9AKMT2AALDH1A1GAA | |
| SCHEMBL19102708 | 0.81 | ACACB (0.38) | MEN1RAB9AKMT2AACACBACACA | |
| SCHEMBL17435570 | 0.81 | MEN1 (0.37) | MEN1RAB9AKMT2AACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |