Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 10/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17435610 | 0.91 | TACR3 (0.36) | TACR3LMNATP53HDAC1ALDH1A1 | |
| SCHEMBL19102694 | 0.91 | TACR3 (0.38) | TACR3LMNATP53HDAC1ALDH1A1 | |
| SCHEMBL19102593 | 0.90 | TACR3 (0.37) | TACR3LMNATP53HDAC1ALDH1A1 | |
| SCHEMBL19102596 | 0.90 | HDAC1 (0.38) | TACR3LMNATP53HDAC1ALDH1A1 | |
| SCHEMBL19102703 | 0.86 | ALDH1A1 (0.38) | TACR3LMNATP53HDAC1ALDH1A1 | |
| SCHEMBL19102752 | 0.85 | TACR3 (0.36) | TACR3LMNATP53HDAC1ALDH1A1 | |
| SCHEMBL17435505 | 0.85 | DHODH (0.39) | TACR3LMNATP53HDAC1ALDH1A1 | |
| SCHEMBL19102597 | 0.84 | HDAC1 (0.37) | TACR3LMNATP53HDAC1ALDH1A1 | |
| SCHEMBL19102591 | 0.84 | ALDH1A1 (0.37) | TACR3LMNATP53HDAC1ALDH1A1 | |
| SCHEMBL17435438 | 0.82 | TACR3 (0.37) | TACR3LMNATP53HDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |