Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | DHODH | Q02127 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17435537 | 0.94 | MEN1 (0.38) | MEN1KMT2ADHODHCYP2C9CYP3A4 | |
| SCHEMBL19102707 | 0.90 | MEN1 (0.38) | MEN1KMT2ADHODHCYP2C9CYP3A4 | |
| SCHEMBL19102708 | 0.86 | ACACB (0.38) | MEN1KMT2ADHODHCYP2C9CYP3A4 | |
| SCHEMBL19102744 | 0.84 | MEN1 (0.38) | MEN1KMT2ADHODHCYP2C9CYP3A4 | |
| SCHEMBL17435570 | 0.84 | MEN1 (0.37) | MEN1KMT2ADHODHCYP2C9CYP3A4 | |
| SCHEMBL19102763 | 0.84 | MEN1 (0.45) | MEN1KMT2ADHODHCYP2C9CYP3A4 | |
| SCHEMBL19102767 | 0.81 | MEN1 (0.43) | MEN1KMT2ADHODHCYP2C9CYP3A4 | |
| SCHEMBL17451824 | 0.80 | MEN1 (0.37) | MEN1KMT2ADHODHCYP2C9CYP3A4 | |
| SCHEMBL17435696 | 0.80 | MEN1 (0.37) | MEN1KMT2ADHODHCYP2C9CYP3A4 | |
| SCHEMBL18100454 | 0.80 | MEN1 (0.37) | MEN1KMT2ADHODHCYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |