Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17453182 | 1.00 | TAS1R3 (0.38) | TAS1R3TAS1R1HDAC1CHRNA7DRD2 | |
| SCHEMBL17435549 | 1.00 | TAS1R3 (0.38) | TAS1R3TAS1R1HDAC1CHRNA7DRD2 | |
| SCHEMBL19102868 | 1.00 | TAS1R3 (0.38) | TAS1R3TAS1R1HDAC1CHRNA7DRD2 | |
| SCHEMBL17451867 | 1.00 | TAS1R3 (0.38) | TAS1R3TAS1R1HDAC1CHRNA7DRD2 | |
| SCHEMBL17435552 | 1.00 | TAS1R3 (0.38) | TAS1R3TAS1R1HDAC1CHRNA7DRD2 | |
| SCHEMBL17451872 | 0.90 | HDAC1 (0.36) | HDAC1CHRNA7HDAC3HDAC4HDAC7 | |
| SCHEMBL17435386 | 0.90 | HDAC1 (0.36) | HDAC1CHRNA7HDAC3HDAC4HDAC7 | |
| SCHEMBL17435384 | 0.90 | HDAC1 (0.36) | HDAC1CHRNA7HDAC3HDAC4HDAC7 | |
| SCHEMBL17435508 | 0.90 | HDAC1 (0.36) | HDAC1CHRNA7HDAC3HDAC4HDAC7 | |
| SCHEMBL19102590 | 0.90 | HDAC1 (0.36) | HDAC1CHRNA7HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |