⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiouracil SCHEMBL29948586 | 1.00 | — | — | |
| Thiouracil SCHEMBL11756790 | 0.87 | — | — | |
| Thiouracil SCHEMBL11777980 | 0.85 | — | — | |
| Methylthiouracil SCHEMBL23628579 | 0.82 | UHRF1 (0.32) | — | |
| Thiouracil SCHEMBL7804099 | 0.82 | DAO (0.30) | — | |
| Thiouracil SCHEMBL11751555 | 0.80 | — | — | |
| Thiouracil SCHEMBL11759356 | 0.77 | MEN1 (0.32) | — | |
| Thiouracil SCHEMBL9097033 | 0.74 | TP53 (0.54) | — | |
| Thiouracil SCHEMBL11759364 | 0.74 | — | — | |
| SCHEMBL467548 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 913 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114651212-B | Positive photosensitive material | 默克专利股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-118507104-B | Low-temperature conductive silver paste and preparation method thereof | 常州碳禾新材料科技有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-118507104-A | Low-temperature conductive silver paste and preparation method thereof | 常州碳禾新材料科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-117729917-A | Combination therapy using AKR1C3 activating compounds and immune checkpoint inhibitors | 深圳艾欣达伟医药科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-108885396-B | Positive working photosensitive material | 默克专利有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115477617-A | Green synthesis method of 2-alkylthio-4,6-dialkoxypyrimidine compound | 南开大学 | 2022-12-16 | — | — | CN | claimed |
| US-20220342308-A1 | POSITIVE WORKING PHOTOSENSITIVE MATERIALS | MERCK PATENT GMBH (DE) | 2022-10-27 | — | — | US | claimed |
| CN-109844641-B | Environmentally stable thick film chemically amplified resists | 默克专利有限公司 | 2022-10-11 | — | — | CN | claimed |
| EP-4058848-A1 | POSITIVE WORKING PHOTOSENSITIVE MATERIAL | Merck Patent GmbH (DE) | 2022-09-21 | — | — | EP | claimed |
| CN-114746753-A | Correlating AKR1C3 enzyme expression level through prostaglandin content and screening administration application | 深圳艾欣达伟医药科技有限公司 | 2022-07-12 | — | — | CN | claimed |
| EP-0148353-B1 | PROCESS FOR THE PREPARATION OF URACIL | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1987-05-27 | — | — | EP | claimed |
| EP-0096561-B1 | STABILIZATION OF SILVER HALIDE EMULSIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-01-21 | — | — | EP | claimed |
| EP-0071018-B1 | PROCESS FOR PREPARING 2,4-DIHYDROXYPYRIMIDINE (URACIL) | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1986-01-08 | — | — | EP | claimed |
| US-4558126-A | Method of preparing uracil | DYNAMIT NOBEL AG (DE) | 1985-12-10 | — | — | US | claimed |
| EP-0148353-A1 | Process for the preparation of uracil | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1985-07-17 | — | — | EP | claimed |
| US-4476306-A | Method of preparing 2,4-dihydroxypyrimidine | DYNAMIT NOBEL AG (DE) | 1984-10-09 | — | — | US | claimed |
| US-4430426-A | BINDER CONTAINING A URACIL AND A SUBSTITUTED PHENOL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-02-07 | — | — | US | claimed |
| EP-0096561-A2 | Stabilization of silver halide emulsions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-12-21 | — | — | EP | claimed |
| EP-0071018-A1 | Process for preparing 2,4-dihydroxypyrimidine (Uracil) | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1983-02-09 | — | — | EP | claimed |
| US-4088751-A | SHAVING CREAM, SHAMPOO, LOTION, 2-THIO-4-OXYPYRIMIDINE OR THIOHYDANTOIN AND HYDROGEN PEROXIDE, EXOTHERMIC REDOX REACTION | COLGATE-PALMOLIVE COMPANY (US) | 1978-05-09 | — | — | US | claimed |