Thiouracil

Thiouracil

SCHEMBL7804099

O=c1[nH][nH]c(=O)[nH]1.Oc1ccnc(S)n1

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiouracil SCHEMBL191107 0.82
Thiouracil SCHEMBL29948586 0.82
Thiouracil SCHEMBL9097033 0.73 TP53 (0.54)
Thiouracil SCHEMBL11756790 0.72
Thiouracil SCHEMBL4958658 0.70 ATAD2 (0.36)
Thiouracil SCHEMBL11777980 0.70
Methylthiouracil SCHEMBL23628579 0.68 UHRF1 (0.32)
Thiouracil SCHEMBL11751555 0.66
Thiouracil SCHEMBL11759356 0.64 MEN1 (0.32)
Uracil SCHEMBL11069645 0.61 CRBN (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100367111-C Lithographic gap-filler forming composition NISSAN CHEMICAL IND LTD (JP) 2008-02-06 CN disclosed
CN-1440518-A Lithographic gap-filler forming composition NISSAN CHEMICAL IND LTD (JP) 2003-09-03 CN disclosed
EP-0823661-B1 Composition for anti-reflective coating material FUJI PHOTO FILM CO LTD (JP) 2001-07-04 EP disclosed
US-6248500-B1 ACRYLIC POLYMERS AND PHENOL, NAPHTHOL OR HYDROXYANTHRACENE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 2001-06-19 US disclosed
US-6090531-A UNDERGOES NO INTERMIXING WITH THE RESIST LAYER, PROVIDES AN EXCELLENT RESIST PATTERN AND SHOWS A HIGHER DRY ETCHING RATE THAN RESIST AND A RESIST PATTERN FORMATION PROCESS FUJI PHOTO FILM CO., LTD. (JP) 2000-07-18 US disclosed
EP-0823661-A1 Composition for anti-reflective coating material FUJI PHOTO FILM CO., LTD. (JP) 1998-02-11 EP disclosed