Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 8/20 | 0.64 |
| ▸ | MMP2 | P08253 | 7/20 | 0.64 |
| ▸ | MMP8 | P22894 | 7/20 | 0.64 |
| ▸ | MMP13 | P45452 | 6/20 | 0.64 |
| ▸ | MMP10 | P09238 | 5/20 | 0.56 |
| ▸ | MMP3 | P08254 | 4/20 | 0.56 |
| ▸ | MMP9 | P14780 | 4/20 | 0.56 |
| ▸ | MMP14 | P50281 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14122875 | 1.00 | MMP12 (0.64) | MMP12MMP2MMP8MMP13MMP10 | |
| SCHEMBL14122164 | 1.00 | MMP12 (0.64) | MMP12MMP2MMP8MMP13MMP10 | |
| SCHEMBL6868588 | 1.00 | MMP12 (0.64) | MMP12MMP2MMP8MMP13MMP10 | |
| SCHEMBL14122758 | 1.00 | MMP12 (0.64) | MMP12MMP2MMP8MMP13MMP10 | |
| SCHEMBL6869090 | 1.00 | MMP12 (0.64) | MMP12MMP2MMP8MMP13MMP10 | |
| SCHEMBL6868685 | 1.00 | MMP12 (0.64) | MMP12MMP2MMP8MMP13MMP10 | |
| SCHEMBL14122841 | 0.92 | MMP12 (0.72) | MMP12MMP2MMP8MMP13MMP10 | |
| SCHEMBL19111742 | 0.92 | MMP12 (0.72) | MMP12MMP2MMP8MMP13MMP10 | |
| SCHEMBL6869529 | 0.92 | MMP12 (0.72) | MMP12MMP2MMP8MMP13MMP10 | |
| SCHEMBL6868541 | 0.92 | MMP12 (0.72) | MMP12MMP2MMP8MMP13MMP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470514-B1 | PSEUDO-DIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-12 | — | — | EP | disclosed |