Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764648 | 1.00 | DPP4 (0.51) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL29972744 | 0.95 | DPP4 (0.56) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL2242130 | 0.93 | DPP4 (0.57) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL2242132 | 0.93 | DPP4 (0.57) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL19696597 | 0.92 | DPP4 (0.53) | DPP4DPP8DPP9BLMGRM8 | |
| SCHEMBL12964861 | 0.92 | DPP4 (0.53) | DPP4DPP8DPP9BLMGRM8 | |
| SCHEMBL17793208 | 0.92 | DPP4 (0.53) | DPP4DPP8DPP9BLMGRM8 | |
| SCHEMBL19374 | 0.90 | FOLH1 (0.55) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL8382466 | 0.90 | FOLH1 (0.55) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL4726036 | 0.90 | FOLH1 (0.55) | DPP4DPP8DPP9BLMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470514-B1 | PSEUDO-DIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-12 | — | — | EP | disclosed |