Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112182 | 1.00 | DPP4 (0.51) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL29972744 | 0.95 | DPP4 (0.56) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL2242130 | 0.93 | DPP4 (0.57) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL2242132 | 0.93 | DPP4 (0.57) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL19696597 | 0.92 | DPP4 (0.53) | DPP4DPP8DPP9BLMGRM8 | |
| SCHEMBL12964861 | 0.92 | DPP4 (0.53) | DPP4DPP8DPP9BLMGRM8 | |
| SCHEMBL17793208 | 0.92 | DPP4 (0.53) | DPP4DPP8DPP9BLMGRM8 | |
| SCHEMBL19374 | 0.90 | FOLH1 (0.55) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL8382466 | 0.90 | FOLH1 (0.55) | DPP4DPP8DPP9BLMALOX15 | |
| SCHEMBL4726036 | 0.90 | FOLH1 (0.55) | DPP4DPP8DPP9BLMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394851-B2 | Osmoprotective complexes for prevention of mitochondrial free radical damage related skin aging | ISLAND KINETICS, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20130028854-A1 | Osmoprotective Complexes for Prevention of Mitochondrial Free Radical Damage Related Skin Aging | ISLAND KINETICS INC. (US) | 2013-01-31 | — | — | US | disclosed |
| US-8314070-B2 | Osmoprotective complexes for prevention of intra-cellular dehydration in mammals | ISLAND KINETICS, INC. (US) | 2012-11-20 | — | — | US | disclosed |
| US-8293943-B1 | Prevention of cellular senescence in mammals by natural peptide complexes | ISLAND KINETICS, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20120264696-A1 | PREVENTION OF CELLULAR SENESCENCE IN MAMMALS BY NATURAL PEPTIDE COMPLEXES | ISLAND KINETICS INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-8258343-B1 | Prevention of cellular senescence in mammals by natural peptide complexes | ISLAND KINETICS, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-8212076-B2 | Prevention of cellular senescence in mammals by natural peptide complexes | Covalence, Inc. (US) | 2012-07-03 | — | — | US | disclosed |
| US-20110190202-A1 | Prevention of Cellular Senescence in Mammals by Natural Peptide Complexes | ISLAND KINETICS INC. (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110124573-A1 | Osmoprotective Complexes for Prevention of Intra-cellular Dehydration in Mammals | ISLAND KINETICS INC. (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124573-A1 | Osmoprotective Complexes for Prevention of Intra-cellular Dehydration in Mammals | GLS2, GOT2, COL14A1 | DPP4 2051/4885DPP8 1742/4885DPP9 2145/4885 |
| US-20120264696-A1 | PREVENTION OF CELLULAR SENESCENCE IN MAMMALS BY NATURAL PEPTIDE COMPLEXES | COL14A1, TP53, CUTA | DPP4 1852/4885DPP8 1533/4885DPP9 2237/4885 |
| US-20130028854-A1 | Osmoprotective Complexes for Prevention of Mitochondrial Free Radical Damage Related Skin Aging | TFAM, HSPA9, TXN2 | DPP4 4482/4885DPP8 4266/4885DPP9 3737/4885 |
| US-20110190202-A1 | Prevention of Cellular Senescence in Mammals by Natural Peptide Complexes | COL14A1, TP53, CUTA | DPP4 1852/4885DPP8 1533/4885DPP9 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.