Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814492 | 0.87 | TAAR1 (0.36) | TAAR1GAATNFRIPK1 | |
| SCHEMBL28035707 | 0.83 | TAAR1 (0.38) | TAAR1GAACYP2A13 | |
| SCHEMBL29395269 | 0.83 | TAAR1 (0.36) | TAAR1GAACYP2A13TNFRIPK1 | |
| SCHEMBL14911877 | 0.83 | TAAR1 (0.36) | TAAR1GAACYP2A13TNFRIPK1 | |
| SCHEMBL10830911 | 0.82 | TAAR1 (0.34) | TAAR1 | |
| SCHEMBL20103788 | 0.81 | TAAR1 (0.59) | TAAR1 | |
| SCHEMBL30004999 | 0.79 | TAAR1 (0.38) | TAAR1GAACYP2A13TNFRIPK1 | |
| SCHEMBL2570460 | 0.79 | TAAR1 (0.38) | TAAR1GAACYP2A13TNFRIPK1 | |
| SCHEMBL2565042 | 0.79 | TAAR1 (0.38) | TAAR1GAACYP2A13TNFRIPK1 | |
| SCHEMBL27766753 | 0.77 | TAAR1 (0.31) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708295-B2 | Substituted 2-aminopyridine protein kinase inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2017-07-18 | — | — | US | disclosed |