Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19315980 | 0.90 | BCL9 (0.48) | BCL9CTNNB1GAAHTR2AMAPT | |
| SCHEMBL763093 | 0.89 | BCL9 (0.54) | BCL9CTNNB1GAAHTR2AMAPT | |
| SCHEMBL15486850 | 0.88 | BCL9 (0.48) | BCL9CTNNB1GAAHTR2AMAPT | |
| SCHEMBL24760264 | 0.83 | HTR2A (0.43) | BCL9CTNNB1GAAHTR2AMAPT | |
| SCHEMBL7080623 | 0.83 | HTR2A (0.53) | BCL9CTNNB1GAAHTR2AMAPT | |
| SCHEMBL903436 | 0.82 | BCL9 (0.52) | BCL9CTNNB1GAAHTR2AMAPT | |
| SCHEMBL6359040 | 0.82 | BCL9 (0.56) | BCL9CTNNB1GAAHTR2AMAPT | |
| SCHEMBL15491284 | 0.82 | GAA (0.49) | BCL9CTNNB1GAAHTR2AMAPT | |
| SCHEMBL13073179 | 0.82 | BCL9 (0.47) | BCL9CTNNB1GAAHTR2AMAPT | |
| SCHEMBL1461897 | 0.82 | ELANE (0.60) | BCL9CTNNB1GAAHTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189840-A1 | METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME | Kempharm, Inc. (US) | 2017-07-12 | — | — | EP | disclosed |